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CA: A Cancer Journal for Clinicians, Vol 12, 188-191, Copyright © 1962 by American Cancer Society

FOCUS

Neuroblastoma, The Unpredictable Tumor

¹ Chairman of the Department of Pediatrics at Memorial Hospital for Cancer and Allied Diseases in New York City.

A recent review of 236 cases of neuroblastoma in children from Memorial Sloan-Kettering Cancer Center, New York City, emphasizes certain features of this disease.

1. The diagnostic difficulties of the clinician, surgeon, radiologist and pathologist may be either simple or extremely complex.

2. Five-year or longer cures have been achieved by surgery alone, irradiation alone, surgery and irradiation combined, and chemotherapy in conjunction with either or both of these conventional and often very successful measures.

3. Unexpected regression has occurred in patients with advanced disease. One patient is surviving over five years, who had no treatment whatsoever. The disease may pursue an unusual course.

4. The prognosis, even in metastatic cases, is guarded.