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CA: A Cancer Journal for Clinicians, Vol 21, 220-226, Copyright © 1971 by American Cancer Society

The Pathology of Tumors, Part Two Biopsy and Diagnostic Cytology

¹ Professor of Surgical Pathology and Pathology, Washington University School of Medicine, and Surgical Pathologist, Barnes Hospital and affiliated hospitals, St. Louis, Missouri.
² Assistant Professor of Pathology, Washington University School of Medicine, and Surgical Pathologist, Barnes Hospital and affiliated hospitals.

Needle, incisional and excisional biopsies, used appropriately, are capable of safely obtaining tissue for microscopic examination from most types of lesions. However, in cases where histologic diagnosis is impossible prior to surgery or radiotherapy, or for detection of asymptomatic cancer of some sites, exfoliative cytology has become an excellent indicator of malignancy, particularly in cervical or endometrial cancer.

We have found that terminology employed in reporting biopsy results is also useful in cytology reports and can give the clinician a clearer idea of the pathologist's findings than the grading system originally used by Papanicolaou.