CA: A Cancer Journal for Clinicians, Vol 21, 342-359, Copyright
© 1971 by American Cancer Society
The Management of Lymphoma
J. E. Ultmann M.D.1
1 Professor of Medicine, Department of Medicine, The University of Chicago, Chicago, Illinois.
Major advances have occurred in the management of patients with lymphoma. These advances have been largely in the area of more precise staging, delivery of more extensive radiotherapy and the optimal use of chemotherapy. Accurate histologic and clinical staging have permitted precise definition of the clinical status of patients and, consequently, more precise application of therapeutic methods to the individual case. The pathophysiology of the complications of lymphoma is now better understood; advances in immunology, in particular, have permitted comprehension of the pathogenesis of infectious complications in patients with lymphoma. In a significant number of selected patients, aggressive radiotherapy promises cure. Although traditional means of chemotherapeutic management have led to significant advances, more aggressive approaches of combination chemotherapy in Hodgkin's disease in particular and probably, in the other lymphomas, too, will lead to significant improvement in remission induction rates and in prolongation of survival.
