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CA: A Cancer Journal for Clinicians, Vol 23, 344-353, Copyright © 1973 by American Cancer Society

Features Suggesting Curability in Lymphoma and Leukemia

¹ The Director of Clinical Investigation, Memorial Sloan-Kettering Cancer Center, New York, New York.

In summary, the features suggesting curability in patients with leukemia and lymphoma are: (1) the curability of patients with certain other types of disseminated neoplastic disease such as trophoblastic tumors and Wilms' tumor; (2) the significant, although so far rather small, five-year survival rate in patients with acute leukemia and Burkitt's tumor; (3) the evidence in man of host resistance against certain tumors such as Burkitt's tumor and localized melanoma; (4) the exciting suggestion of the possible value of active specific or nonspecific immunotherapy in patients with acute leukemia; and (5) the evidence of a much higher wave of long-term emissions following new and more intensive combination therapy in patients with both acute leukemia and Burkitt's tumor. It would be surprising indeed if these series of patients now under treatment with both chemotherapy and immunotherapy did not produce significantly higher five-year and indefinite survival figures than those at present.