CA: A Cancer Journal for Clinicians, Vol 24, 363-367, Copyright
© 1974 by American Cancer Society
Resection of Head of Pancreas and Duodenum for CarcinomaPancreatoduodenectomy
Alexander Brunschwig M.D.
A case history is presented to show the feasibility of excision of the entire head of the pancreas and practically all of the duodenum for carcinoma of the head of the pancreas. Such an operation might also be performed for primary malignant tumors of the duodenum.
While no gross evidence of metastases was present at the time of the operations, the patient died 85 days following excision and, at necropsy, carcinomatosis of the peritoneal cavity and multiple liver metastases were found. Gross and histological examination of the liver, stomach, and small bowel revealed no evidence that the removal of practically the entire duodenum had resulted in significant metabolic disturbances during the period of survival.