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CA Cancer J Clin 1983; 33:167-171
doi: 10.3322/canjclin.33.3.167
© 1983 American Cancer Society
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CA: A Cancer Journal for Clinicians, Vol 33, 167-171, Copyright © 1983 by American Cancer Society

Metastatic Islet Cell Carcinoma: A Potentially Treatable Cause of "Carcinoma of Unknown Origin"

Alan B. Weitberg M.D.1 and Sigmund A. Weitzman M.D.2

1 Instructor in Medicine at the Hematology-Oncology Unit of Massachusetts General Hospital. Harvard Medical School, in Boston, Massachusetts.
2 Assistant Professor of Medicine at the Hematology-Oncology Unit of Massachusetts General Hospital, Harvard Medical School, in Boston, Massachusetts.

A 55-year-old woman presented with diplopia secondary to an orbital mass. Physical examination showed a large ovarian mass. Further evaluation revealed these lesions to be metastases from a nonfunctioning pancreatic islet cell carcinoma, the first such case reported. Since these tumors can be responsive to chemotherapy, it is important to consider islet cell cancers in patients presenting with "metastatic carcinoma of unknown origin."






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Copyright © 1983 by American Cancer Society.