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CA Cancer J Clin 1984; 34:2-6
doi: 10.3322/canjclin.34.1.2
© 1984 American Cancer Society
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CA: A Cancer Journal for Clinicians, Vol 34, 2-6, Copyright © 1984 by American Cancer Society

The Problem of Nausea and Vomiting in Modem Cancer Chemotherapy

John R. Durant M.D.1

1 President of the Fox Chase Cancer Center in Philadelphia, Pennsylvania.

Unfortunately, a successful program for a given patient is often discovered only by trial and error about the time treatment ends. We must insist on a more rational approach for preventing nausea and vomiting based on fundamental pathophysiologic and pharmacologic information about the anatomic sites of action and the biochemistry and pharmacology of the agents involved. For the moment, there are no generally useful panaceas. If our treatment programs are to do the most good, we must learn more not only about their therapeutic efficacy but how to improve the therapeutic ratio by reducing side effects without a compromise in efficacy.






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Copyright © 1984 by American Cancer Society.