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CA: A Cancer Journal for Clinicians, Vol 34, 110-117, Copyright © 1984 by American Cancer Society

Primary Cardiac Osteosarcoma: Multidisciplinary Aspects Applicable to Extraskeletal Osteosarcoma Generally

¹ Assistant Professor of Pathology and Internal Medicine, and Director of the Autopsy Service of the University of Connecticut Health Center in Farmington, Connecticut.
² Professor and Vice-Chairman of the Department of Diagnostic Radiology and Nuclear Medicine at Rush-Presbyterian-St. Luke's Medical Center and Rush Medical College in Chicago, Illinois.
³ Resident in Surgery at Loyola University Medical Center in Maywood, Illinois.
⁴ Associate Professor in the Department of Internal Medicine at Rush-Presbyterian-St. Luke's Medical Center and Rush Medical College in Chicago, Illinois.
⁵ Research Assistant in the Department of Pathology at Rush-Presbyterian-St. Luke's Medical Center and Rush Medical College in Chicago, Illinois.

An osteosarcoma, primary in the right ventricular epicardium, produced pericardial constriction. Intense activity on technetium-99m bone scintigraphy led to a correct preoperative diagnosis. Biopsy of unrepresentative tissue clouded the diagnosis, and autopsy resolved the issue. Several clinicopathologic correlations are presented. Major therapeutic advances mandate early recognition of extraskeletal osteosarcoma, and the topic is reviewed in regard to cardiac cancers in general. The need to biopsy both hard and fleshy areas of unusual tumors is reviewed.

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