CA: A Cancer Journal for Clinicians, Vol 37, 291-301, Copyright
© 1987 by American Cancer Society
Bone Marrow Transplantation
E. Donnall Thomas MD1
1 Professor of Medicine at the University of Washington School of Medicine, and Associate Director for Clinical Research at the Fred Hutchinson Cancer Research Center, in Seattle, Washington.
Marrow transplantation has clearly been established as a therapeutic modality for a wide range of diseases. There are now a number of centers in the United States and in Europe with the capability of carrying out these transplants. Each patient must be evaluated individually, and the patient, the potential donor, and the family must be fully informed of both the benefits and expected complications. Enormous progress has been made in the past 10 years, and this progress will undoubtedly continue as more and more centers continue to explore new regimens and compare results. Despite the risks and complications, marrow transplantation still offers the only potential cure for many patients with hematologic disorders.