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CA: A Cancer Journal for Clinicians, Vol 38, 362-367, Copyright © 1988 by American Cancer Society

Sacrococcygeal Teratomas

¹ Head of the Division of Pediatric Surgery of Childrens Hospital of Los Angeles, and Professor of Surgery at the University of Southern California School of Medicine, in Los Angeles, California.

In conclusion, treatment of malignant sacrococcygeal teratoma remains a problem, and the prognosis for patients with this disease is poor. Recurrence after excision of an overtly malignant tumor is common and carries a high risk of mortality. Long-term survival of patients with recurrent malignant sacrococcygeal teratoma is rare regardless of the therapy used. Aggressive surgical therapy is recommended. Adjuvant chemotherapy and radiotherapy should be used, although the ideal combination of agents remains to be determined. Postoperative therapy is best formulated in a tumor-board setting with appropriate input by knowledgeable surgeons, radiotherapists, and oncologists. Through cooperative tive efforts and careful follow-up, the best methods of therapy can be formulated to help increase the survival of patients with malignant sacrococcygeal teratomas.

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