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CA: A Cancer Journal for Clinicians, Vol 4, 164-166, Copyright © 1954 by American Cancer Society

Leukoplakia Buccalis

¹ The Department of Dermatology and Syphilology of the New York University—Post-Graduate Medical School and the Skin and Cancer Unit of the New York University Hospital, New York, New York.

1. Leukoplakia of the oral cavity is essentially produced by factors causing chronic irritation such as smoking, malocclusion, ill-fitting dentures, rough tooth edges, betel-nut chewing, and the like. Smoking in leukoplakia, as in cancer of the lung, is considered a major cause.

2. Good oral hygiene should be maintained and chronic irritating factors eliminated.

3. Each case of leukoplakia should be considered individually. Signs of beginning malignant changes are fissuring, ulceration, and cracking and require definitive treatment. Preferred specific methods of treatment include surgical excision or complete destruction by electrodesiccation or electrocoagulation.