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CA: A Cancer Journal for Clinicians, Vol 44, Issue 4 211-247, Copyright © 1994 by American Cancer Society

ARTICLES

Pediatric soft tissue sarcomas

L. H. Wexler and L. J. Helman
Solid Tumor Section, National Cancer Institute, Bethesda, Maryland.

Soft tissue sarcomas are the sixth most common cancer in children and collectively account for about seven percent of all pediatric cancers. The development of increasingly intensive, multimodality treatment protocols for these tumors has led to a steady increase in cure rates for these neoplasms, especially for rhabdomyosarcoma, the most common pediatric soft tissue sarcoma. This article provides an overview of the basic biology, clinical management, and clinical research for pediatric soft tissue sarcomas.

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