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CA: A Cancer Journal for Clinicians, Vol 45, Issue 3 179-192, Copyright © 1995 by American Cancer Society
K. K. Matthay
Neuroblastoma is the third most common malignancy in childhood and accounts
for at least 15 percent of cancer-related deaths in children. The varied
clinical behavior of this disease, ranging from spontaneous regression in
some to progression while under aggressive therapy in others, has been
associated with various biologic differences, providing insight into
pathophysiology and possibilities for more specific treatments. This
article reviews the epidemiology, pathophysiology, clinical evaluation, and
treatment of neuroblastoma.
ARTICLES
Neuroblastoma: a clinical challenge and biologic puzzle
University of California School of Medicine, San Francisco, USA.
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