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CA: A Cancer Journal for Clinicians, Vol 47, Issue 1 52-64, Copyright © 1997 by American Cancer Society

ARTICLES

Pathobiological considerations relating to the treatment of intraductal carcinoma (ductal carcinoma in situ) of the breast

E. R. Fisher
National Surgical Adjuvant Breast and Bowel Project, Shadyside Hospital, Pittsburgh, Pennsylvania, USA.

Management of ductal carcinoma in situ has become one of the most controversial topics in breast disease. While mastectomy has been the traditional treatment, many now feel it is excessive in most cases. As a result, a great effort has been made to identify pathobiological characteristics of DCIS that can be used to stratify appropriate treatment decisions. This article reviews efforts to relate pathobiological characteristics to disease management and provides treatment recommendations based on the latest evidence.

This article has been cited by other articles:

				E. R. Fisher and B. Fisher Relation of a Recurrent Intraductal Carcinoma (Ductal Carcinoma In Situ) to the Primary Tumor J Natl Cancer Inst, February 16, 2000; 92(4): 288 - 289. [Full Text] [PDF]

				B. S. Reddy, T. Kawamori, R. A. Lubet, V. E. Steele, G. J. Kelloff, and C. V. Rao Chemopreventive Efficacy of Sulindac Sulfone against Colon Cancer Depends on Time of Administration during Carcinogenic Process Cancer Res., July 1, 1999; 59(14): 3387 - 3391. [Abstract] [Full Text] [PDF]