CA: A Cancer Journal for Clinicians, Vol 48, Issue 2 67-68, Copyright © 1998 by American Cancer Society
Historical perspective on nutritional support of cancer patients
E. M. Copeland 3rd
Initially, total parenteral nutrition (TPN) was not used in cancer patients
because of the fear of sepsis and the potential for stimulation of tumor
growth. It was used first in cancer patients who had failed all attempts at
enteral nutrition and in whom adequate anticancer therapy would have been
otherwise impossible. TPN candidates today remain patients with responsive
tumors who cannot tolerate the toxicity of cancer therapy because they are
malnourished.