HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE COVER ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Submit a letter to the editor Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Vikram, B. Search for Related Content PubMed PubMed Citation Articles by Vikram, B.

CA: A Cancer Journal for Clinicians, Vol 48, Issue 4 199-209, Copyright © 1998 by American Cancer Society

ARTICLES

Adjuvant therapy in head and neck cancer

B. Vikram
Unified Department of Radiation Oncology, Albert Einstein College of Medicine, Bronx, NY, USA.

Many challenges remain, but considerable progress has been made in this field since 1983, when we published in this journal an article titled "Adjuvant Radiation Therapy in Locally Advanced Head and Neck Cancer." Several clinical and pathologic features have been identified that can stratify patients according to the risk of relapse (whether at the primary site, in the neck, or at distant sites) or the risk of second cancers, so that additional adjuvant treatment might be administered only to patients who are the most likely to benefit from it. Hope exists that in the near future our capabilities will be bolstered by the availability of powerful new biologic and molecular genetic tools. The greatest advance, perhaps, has been the recognition that adjuvant therapy for head and neck cancer should not be an afterthought but part of a thoughtfully crafted interdisciplinary strategy aimed at maximizing tumor control with the least morbidity.

This article has been cited by other articles:

				Q. Sun, T. Sakaida, W. Yue, S. M. Gollin, and J. Yu Chemosensitization of head and neck cancer cells by PUMA Mol. Cancer Ther., December 1, 2007; 6(12): 3180 - 3188. [Abstract] [Full Text] [PDF]