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CA Cancer J Clin 2001; 51:92
doi: 10.3322/canjclin.51.2.92
© 2001 American Cancer Society
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Cervical Cancer: Prevention, Diagnosis, and Therapeutics

Mike F. Janicek, MD and Hervy E. Averette, MD

Dr. Janicek is a recipient of an American Cancer Society Career Development Award and served as Assistant Professor of Obstetrics & Gynecology and Assistant Professor of Microbiology & Immunology at the University of Miami School of Medicine. He is currently President of OncoGyne, PC in Phoenix, AZ.
Dr. Averette is Sylvester Professor and American Cancer Society Professor, and Director of Gynecologic Oncology at the University of Miami School of Medicine, Miami, FL.

Cervical cancer is a leading cause of cancer deaths in women worldwide. Because of its association with human papilloma virus infection, as well as the ability to screen for premalignant stages of the disease, it is now largely a preventable disease. This article describes the molecular basis for cervical cancer, and presents a clinical overview of current treatment approaches and technological advances, emphasizing the unique aspects of this viral disease as it relates to the immune system and vaccination or other immunotherapeutic strategies.




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