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Dr. Ford is Associate Director for Clinical Research, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD.
Dr. Minasian is Chief, Community Oncology and Prevention Trials Research Group and Program Director for the Selenium and Vitamin E Cancer Prevention Trial (SELECT), Division of Cancer Prevention, National Cancer Institute, Bethesda, MD.
Dr. McCaskill-Stevens is Program Director in the Community Oncology and Prevention Trials Research Group and Program Director for the Study of Tamoxifen and Raloxifene (STAR), Division of Cancer Prevention, National Cancer Institute, Bethesda, MD.
Dr. Pisano is Professor, Radiology and Biomedical Engineering, University of North Carolina School of Medicine, Chapel Hill, NC.
Dr. Sullivan is Associate Director, Biomedical Imaging Program/ Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD.
Dr. Smith is Director, Cancer Screening, Cancer Control Science Department, American Cancer Society, Atlanta, GA.
Enrollment into cancer prevention and early detection clinical trials represents a unique challenge compared with a diagnostic or treatment trial because it involves subjects without a diagnosis of cancer. This paper examines some of the barriers to participation in prevention and early detection trials and provides detailed information about two ongoing prevention and two ongoing early detection clinical trials open to enrollment as well as brief summaries of seven additional trials now open to enrollment.
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