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Dr. Jemal is Strategic Director, Cancer Surveillance, Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA.
Ms. Siegel is Manager, Surveillance Information Services, Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA.
Dr. Ward is Managing Director, Surveillance Research, Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA.
Dr. Hao is Senior Epidemiologist, Surveillance Research, Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA.
Dr. Xu is Epidemiologist, Mortality Statistics Branch, Division of Vital Statistics, National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD.
Mr. Murray is Manager, Surveillance Data Systems, Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA.
Dr. Thun is Vice President, Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA.
Published online through CA First Look at http://CAonline.AmCancerSoc.org.
Each year, the American Cancer Society estimates the number of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data on cancer incidence, mortality, and survival based on incidence data from the National Cancer Institute, Centers for Disease Control and Prevention, and the North American Association of Central Cancer Registries and mortality data from the National Center for Health Statistics. Incidence and death rates are age-standardized to the 2000 US standard million population. A total of 1,437,180 new cancer cases and 565,650 deaths from cancer are projected to occur in the United States in 2008. Notable trends in cancer incidence and mortality include stabilization of incidence rates for all cancer sites combined in men from 1995 through 2004 and in women from 1999 through 2004 and a continued decrease in the cancer death rate since 1990 in men and since 1991 in women. Overall cancer death rates in 2004 compared with 1990 in men and 1991 in women decreased by 18.4% and 10.5%, respectively, resulting in the avoidance of over a half million deaths from cancer during this time interval. This report also examines cancer incidence, mortality, and survival by site, sex, race/ethnicity, education, geographic area, and calendar year, as well as the proportionate contribution of selected sites to the overall trends. Although much progress has been made in reducing mortality rates, stabilizing incidence rates, and improving survival, cancer still accounts for more deaths than heart disease in persons under age 85 years. Further progress can be accelerated by supporting new discoveries and by applying existing cancer control knowledge across all segments of the population.
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E. C. Ford, J. Herman, E. Yorke, and R. L. Wahl 18F-FDG PET/CT for Image-Guided and Intensity-Modulated Radiotherapy J. Nucl. Med., October 1, 2009; 50(10): 1655 - 1665. [Abstract] [Full Text] [PDF]
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Z. Li, Z. Chang, L. J. Chiao, Y. Kang, Q. Xia, C. Zhu, J. B. Fleming, D. B. Evans, and P. J. Chiao TrkBT1 Induces Liver Metastasis of Pancreatic Cancer Cells by Sequestering Rho GDP Dissociation Inhibitor and Promoting RhoA Activation Cancer Res., October 1, 2009; 69(19): 7851 - 7859. [Abstract] [Full Text] [PDF]
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G. Konstantinidou, E. A. Bey, A. Rabellino, K. Schuster, M. S. Maira, A. F. Gazdar, A. Amici, D. A. Boothman, and P. P. Scaglioni Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Blockade Is an Effective Radiosensitizing Strategy for the Treatment of Non-Small Cell Lung Cancer Harboring K-RAS Mutations Cancer Res., October 1, 2009; 69(19): 7644 - 7652. [Abstract] [Full Text] [PDF]
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Y. Liu, P. Liu, W. Wen, M. A. James, Y. Wang, J. E. Bailey-Wilson, C. I. Amos, S. M. Pinney, P. Yang, M. de Andrade, et al. Haplotype and Cell Proliferation Analyses of Candidate Lung Cancer Susceptibility Genes on Chromosome 15q24-25.1 Cancer Res., October 1, 2009; 69(19): 7844 - 7850. [Abstract] [Full Text] [PDF]
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 S. AL-SAAD, T. DONNEM, K. AL-SHIBLI, M. PERSSON, R. M. BREMNES, and L.-T. BUSUND Diverse Prognostic Roles of Akt Isoforms, PTEN and PI3K in Tumor Epithelial Cells and Stromal Compartment in Non-small Cell Lung Cancer Anticancer Res, October 1, 2009; 29(10): 4175 - 4183. [Abstract] [Full Text] [PDF]
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B. WEBER, A. LORTHOLARY, F. MAYER, H. BOURGEOIS, H. ORFEUVRE, M. COMBE, C. PLATINI, J. CRETIN, D. FRIC, D. PARAISO, et al. Pegylated Liposomal Doxorubicin and Carboplatin in Late-relapsing Ovarian Cancer: A GINECO Group Phase II Trial Anticancer Res, October 1, 2009; 29(10): 4195 - 4200. [Abstract] [Full Text] [PDF]
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Y. W. MOON, J. H. SOHN, Y. T. KIM, H. CHANG, J. H. JEONG, Y. J. LEE, J. CHANG, S. K. KIM, M. JUNG, S. HONG, et al. Adenosine Triphosphate-based Chemotherapy Response Assay (ATP-CRA)-guided versus Empirical Chemotherapy in Unresectable Non-small Cell Lung Cancer Anticancer Res, October 1, 2009; 29(10): 4243 - 4249. [Abstract] [Full Text] [PDF]
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 K K WONG, N ZARZHEVSKY, J M CAHILL, K A FREY, and A M AVRAM Hybrid SPECT-CT and PET-CT imaging of differentiated thyroid carcinoma Br. J. Radiol., October 1, 2009; 82(982): 860 - 876. [Abstract] [Full Text] [PDF]
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 T. C. Schirmang, W. W. Mayo-Smith, D. E. Dupuy, M. D. Beland, and D. J. Grand Kidney Neoplasms: Renal Halo Sign after Percutaneous Radiofrequency Ablation--Incidence and Clinical Importance in 101 Consecutive Patients Radiology, October 1, 2009; 253(1): 263 - 269. [Abstract] [Full Text] [PDF]
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 I. S. Zagon, R. N. Donahue, and P. J. McLaughlin Opioid growth factor-opioid growth factor receptor axis is a physiological determinant of cell proliferation in diverse human cancers Am J Physiol Regulatory Integrative Comp Physiol, October 1, 2009; 297(4): R1154 - R1161. [Abstract] [Full Text] [PDF]
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N. Takahashi-Shiga, H. Utsunomiya, Y. Miki, S. Nagase, R. Kobayashi, M. Matsumoto, H. Niikura, K. Ito, and N. Yaegashi Local Biosynthesis of Estrogen in Human Endometrial Carcinoma through Tumor-Stromal Cell Interactions Clin. Cancer Res., October 1, 2009; 15(19): 6028 - 6034. [Abstract] [Full Text] [PDF]
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 J. Landa and L. H. Schwartz Contemporary Imaging in Sarcoma Oncologist, October 1, 2009; 14(10): 1021 - 1038. [Abstract] [Full Text] [PDF]
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R. Zhao, J. Zhu, X. Ji, J. Cai, F. Wan, Q. Li, B. Zhong, S. Tucker, and D. Wang A Phase II Study of Irinotecan and Capecitabine for Patients with Unresectable Liver-only Metastases from Colorectal Cancer Jpn. J. Clin. Oncol., September 22, 2009; (2009) hyp114v1. [Abstract] [Full Text] [PDF]
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R. Schlaberg, D. J. Choe, K. R. Brown, H. M. Thaker, and I. R. Singh XMRV is present in malignant prostatic epithelium and is associated with prostate cancer, especially high-grade tumors PNAS, September 22, 2009; 106(38): 16351 - 16356. [Abstract] [Full Text] [PDF]
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S. L. Ellard, M. Clemons, K. A. Gelmon, B. Norris, H. Kennecke, S. Chia, K. Pritchard, A. Eisen, T. Vandenberg, M. Taylor, et al. Randomized Phase II Study Comparing Two Schedules of Everolimus in Patients With Recurrent/Metastatic Breast Cancer: NCIC Clinical Trials Group IND.163 J. Clin. Oncol., September 20, 2009; 27(27): 4536 - 4541. [Abstract] [Full Text] [PDF]
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G. Rennert, H. S. Rennert, M. Pinchev, O. Lavie, and S. B. Gruber Use of Hormone Replacement Therapy and the Risk of Colorectal Cancer J. Clin. Oncol., September 20, 2009; 27(27): 4542 - 4547. [Abstract] [Full Text] [PDF]
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F. Cappuzzo, G. Tallini, G. Finocchiaro, R. S. Wilson, C. Ligorio, L. Giordano, L. Toschi, M. Incarbone, R. Cavina, L. Terracciano, et al. Insulin-like growth factor receptor 1 (IGF1R) expression and survival in surgically resected non-small-cell lung cancer (NSCLC) patients Ann. Onc., September 18, 2009; (2009) mdp357v1. [Abstract] [Full Text] [PDF]
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A. S. Dobroff, H. Wang, V. O. Melnikova, G. J. Villares, M. Zigler, L. Huang, and M. Bar-Eli Silencing cAMP-response Element-binding Protein (CREB) Identifies CYR61 as a Tumor Suppressor Gene in Melanoma J. Biol. Chem., September 18, 2009; 284(38): 26194 - 26206. [Abstract] [Full Text] [PDF]
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Y.-H. Shao, K. Demissie, W. Shih, A. R. Mehta, M. N. Stein, C. B. Roberts, R. S. DiPaola, and G. L. Lu-Yao Contemporary Risk Profile of Prostate Cancer in the United States J Natl Cancer Inst, September 16, 2009; 101(18): 1280 - 1283. [Abstract] [Full Text] [PDF]
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M. Gwinn, I. Guessous, and M. J. Khoury Invited Commentary: Genes, Environment, and Hybrid Vigor Am. J. Epidemiol., September 15, 2009; 170(6): 703 - 707. [Abstract] [Full Text] [PDF]
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