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CA Cancer J Clin 2009; 59:99-110
doi: 10.3322/caac.20014
© 2009 American Cancer Society
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 Thyroid Aspiration Cytology: Current Status
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Thyroid Aspiration Cytology: Current Status

Lester J. Layfield, MD1, Edmund S. Cibas, MD2, Hossein Gharib, MD3 and Susan J. Mandel, MD, MPH4

1Professor and Head, Anatomic Pathology, University of Utah School of Medicine, University of Utah Hospital and Clinics, Salt Lake City, UT
2Associate Professor of Pathology, Harvard Medical School Director of the Division of Cytopathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
3Professor of Medicine, Department of Endocrinology, Mayo Clinic College of Medicine, Rochester, MN
4Professor of Medicine, Associate Chief of the Division of Endocrinology, Diabetes and Metabolism, Hospital of the University of Pennsylvania, Philadelphia, PA

Corresponding author: Lester J. Layfield, MD, Department of Pathology, Huntsman Cancer Hospital, 1950 Circle of Hope, Room 3860, Salt Lake City, UT 84112; e-mail: layfiel{at}aruplab.com

To earn free CME credit or nursing contact hours for successfully completing the online quiz based on this article, go to http://CME.AmCancerSoc.org.

DISCLOSURES: Dr. Gharib received a research grant from Genzyme Corporation for research completed in 2008. No other conflict of interest relevant to this article was reported.

In the adult population, thyroid nodules are common and are increasingly detected by ultrasound examination or other scanning techniques. Depending on their size and ultrasonographic features, these nodules may require further investigation, including tissue diagnosis. Fine-needle aspiration (FNA) has become the predominant method to obtain tissue for microscopic analysis. In October 2007, the National Cancer Institute sponsored a conference to review the state of the science for the use of FNA in the management of thyroid nodules. This conference reviewed indications for thyroid FNA and pre-FNA requirements, training and credentialing, techniques for thyroid FNA, diagnostic terminology and morphologic criteria, utilization of ancillary studies, and post-FNA testing and treatment options. The results of those discussions have been published in both print and electronic versions. The aim of the current article was to discuss indications for FNA, diagnostic terminology, and post-FNA options, issues that are important to physicians who are managing patients with thyroid nodules. CA Cancer J Clin 2009;59:99–110. © 2009 American Cancer Society, Inc.




eLetters:

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Thyroid Fine Needle Cytology: A Look to the Needle
Carlo Cappelli, et al.
CA Online, 8 Apr 2009 [Full text]

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