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CA: A Cancer Journal for Clinicians, Vol 8, 66-68, Copyright © 1958 by American Cancer Society

Tobacco Smoking and Cancer of the Lung

Statement of the [British] Medical Research Council

1. A very great increase has occurred during the past twenty-five years in the death-rate from lung cancer in Great Britain and other countries.

2. A relatively small number of the total cases can be attributed to specific industrial hazards.

3. A proportion of cases, the exact extent of which cannot yet be defined, may be due to atmospheric pollution.

4. Evidence from many investigations in different countries indicates that a major part of the increase is associated with tobacco smoking, particularly in the form of cigarettes. In the opinion of the Council, the most reasonable interpretation of this evidence is that the relationship is one of direct cause and effect.

5. The identification of several carcinogenic substances in tobacco smoke provides a rational basis for such a causal relationship.