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Published online before print June 29, 2009
CA Cancer J Clin 2009; 59:264-273
doi: 10.3322/caac.20026
© 2009 American Cancer Society
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Screening for Prostate Cancer
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Screening for Prostate Cancer

Otis W. Brawley, MD1, Donna P. Ankerst, PhD2 and Ian M. Thompson, MD3

1Chief Medical Officer, American Cancer Society, Atlanta, GA
2Research Associate Professor, Departments of Urology, Epidemiology, and Biostatistics, The University of Texas Health Science Center at San Antonio, San Antonio, TX
3Professor and Chairman, Department of Urology, The University of Texas Health Science Center at San Antonio, San Antonio, TX

Corresponding author: Ian M. Thompson, MD, Department of Urology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229; thompsoni{at}uthscsa.edu

To earn free CME credit or nursing contact hours for successfully completing the online quiz based on this article, go to http://CME.AmCancerSoc.org.

DISCLOSURES: Dr. Thompson serves as a consultant to Veridex. No other conflict of interest relevant to this article was reported.

In the United States, prostate cancer will affect 1 man in 6 during his lifetime. Since the mid-1980s, screening with the prostate–specific antigen (PSA) blood test has more than doubled the risk of a prostate cancer diagnosis. A decrease in prostate cancer death rates has been observed since that time, but the relative contribution of PSA testing as opposed to other factors, such as improved treatment, has been uncertain. The recent release of 2 large randomized trials suggests that if there is a benefit of screening, it is, at best, small. Methods to assess a man's risk of prostate cancer, including those tools that integrate multiple risk factors, are now available and should be used in risk assessment. Men undergoing screening for prostate cancer may reduce their risk of prostate cancer with finasteride. CA Cancer J Clin 2009;59:264-273. © 2009 American Cancer Society, Inc.




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Comments:

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Misinterpreting prostate screening trial results
Stefano Ciatto
CA Online, 27 Jul 2009 [Full text]
"Primum nocere": Don’t touch my prostate!
Alain Braillon
CA Online, 28 Jul 2009 [Full text]
eLetter to "Screening for Prostate Cancer"
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