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Published online before print May 27, 2009
CA Cancer J Clin 2009
doi: 10.3322/caac.20006
© 2009 American Cancer Society
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Cancer Statistics, 2009

Ahmedin Jemal, DVM, PhD1, Rebecca Siegel, MPH2, Elizabeth Ward, PhD3, Yongping Hao, PhD4, Jiaquan Xu, MD5 and Michael J. Thun, MD, MS6

1Strategic Director, Cancer Surveillance, Surveillance and Health Policy Research, American Cancer Society, Atlanta, Georgia
2Manager, Surveillance Information Services, Surveillance and Health Policy Research, American Cancer Society, Atlanta, Georgia
3Vice President, Surveillance and Health Policy Research, American Cancer Society, Atlanta, Georgia
4Senior Epidemiologist, Surveillance and Health Policy Research, American Cancer Society, Atlanta, Georgia
5Epidemiologist, Mortality Statistics Branch, Division of Vital Statistics, National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland
6Vice President Emeritus, Epidemiology and Surveillance Research, American Cancer Society, Atlanta, Georgia

Corresponding author: Ahmedin Jemal, DVM, PhD, Surveillance and Health Policy Research, American Cancer Society, 250 Williams Street, NW, Atlanta, GA 30303-1002; ahmedin.jemal{at}cancer.org

DISCLOSURES: The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the Centers for Disease Control and Prevention. The authors report no conflicts of interest.

Each year, the American Cancer Society estimates the number of new cancer cases and deaths expected in the United States in the current year and compiles the most recent data on cancer incidence, mortality, and survival based on incidence data from the National Cancer Institute, Centers for Disease Control and Prevention, and the North American Association of Central Cancer Registries and mortality data from the National Center for Health Statistics. Incidence and death rates are standardized by age to the 2000 United States standard million population. A total of 1,479,350 new cancer cases and 562,340 deaths from cancer are projected to occur in the United States in 2009. Overall cancer incidence rates decreased in the most recent time period in both men (1.8% per year from 2001 to 2005) and women (0.6% per year from 1998 to 2005), largely because of decreases in the three major cancer sites in men (lung, prostate, and colon and rectum [colorectum]) and in two major cancer sites in women (breast and colorectum). Overall cancer death rates decreased in men by 19.2% between 1990 and 2005, with decreases in lung (37%), prostate (24%), and colorectal (17%) cancer rates accounting for nearly 80% of the total decrease. Among women, overall cancer death rates between 1991 and 2005 decreased by 11.4%, with decreases in breast (37%) and colorectal (24%) cancer rates accounting for 60% of the total decrease. The reduction in the overall cancer death rates has resulted in the avoidance of about 650,000 deaths from cancer over the 15-year period. This report also examines cancer incidence, mortality, and survival by site, sex, race/ethnicity, education, geographic area, and calendar year. Although progress has been made in reducing incidence and mortality rates and improving survival, cancer still accounts for more deaths than heart disease in persons younger than 85 years of age. Further progress can be accelerated by applying existing cancer control knowledge across all segments of the population and by supporting new discoveries in cancer prevention, early detection, and treatment. CA Cancer J Clin 2009. © 2009 American Cancer Society, Inc.




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L. Cheng, A. V. Ramesh, A. Flesken-Nikitin, J. Choi, and A. Yu. Nikitin
Mouse Models for Cancer Stem Cell Research
Toxicol Pathol, January 1, 2010; 38(1): 62 - 71.
[Abstract] [Full Text] [PDF]

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 Cancer Prevention ResearchHome page
M. D. Iniesta, J. Chien, M. Wicha, and S. D. Merajver
One-Hit Effects and Cancer
Cancer Prevention Research, January 1, 2010; 3(1): 12 - 15.
[Abstract] [Full Text] [PDF]

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 Toxicol PatholHome page
T. Maziasz, V. J. Kadambi, L. Silverman, E. Fedyk, and C. L. Alden
Predictive Toxicology Approaches for Small Molecule Oncology Drugs
Toxicol Pathol, January 1, 2010; 38(1): 148 - 164.
[Abstract] [Full Text] [PDF]

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 Clin. Chem.Home page
S. J. Freedland, C. D. Williams, and E. M. Masko
Adiponectin and Prostate Cancer Mortality: To Be or Not to Be Skinny?
Clin. Chem., January 1, 2010; 56(1): 1 - 3.
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 Clin. Cancer Res.Home page
A. J. Armstrong, E. Garrett-Mayer, R. de Wit, I. Tannock, and M. Eisenberger
Prediction of Survival following First-Line Chemotherapy in Men with Castration-Resistant Metastatic Prostate Cancer
Clin. Cancer Res., January 1, 2010; 16(1): 203 - 211.
[Abstract] [Full Text] [PDF]

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 Clin. Cancer Res.Home page
Y. Su, K. I. Amiri, L. W. Horton, Y. Yu, G. D. Ayers, E. Koehler, M. C. Kelley, I. Puzanov, A. Richmond, and J. A. Sosman
A Phase I Trial of Bortezomib with Temozolomide in Patients with Advanced Melanoma: Toxicities, Antitumor Effects, and Modulation of Therapeutic Targets
Clin. Cancer Res., January 1, 2010; 16(1): 348 - 357.
[Abstract] [Full Text] [PDF]

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 The OncologistHome page
B. Vincenzi, D. Santini, A. Russo, R. Addeo, F. Giuliani, L. Montella, S. Rizzo, O. Venditti, A. M. Frezza, M. Caraglia, et al.
Early Skin Toxicity as a Predictive Factor for Tumor Control in Hepatocellular Carcinoma Patients Treated with Sorafenib
Oncologist, January 1, 2010; 15(1): 85 - 92.
[Abstract] [Full Text] [PDF]

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 Ann OncolHome page
Y. Kawai, S. Sakano, Y. Suehiro, T. Okada, Y. Korenaga, T. Hara, K. Naito, H. Matsuyama, and Y. Hinoda
Methylation level of the RASSF1A promoter is an independent prognostic factor for clear-cell renal cell carcinoma
Ann. Onc., December 27, 2009; (2009) mdp577v1.
[Abstract] [Full Text] [PDF]

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 NEJMHome page
P. Sharma
Barrett's Esophagus
N. Engl. J. Med., December 24, 2009; 361(26): 2548 - 2556.
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 NEJMHome page
A. H. Partridge and E. P. Winer
On Mammography -- More Agreement Than Disagreement
N. Engl. J. Med., December 24, 2009; 361(26): 2499 - 2501.
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 Cancer Res.Home page
H. Fukushima, F. Koga, S. Kawakami, Y. Fujii, S. Yoshida, E. Ratovitski, B. Trink, and K. Kihara
Loss of {Delta}Np63{alpha} Promotes Invasion of Urothelial Carcinomas via N-Cadherin/Src Homology and Collagen/Extracellular Signal-Regulated Kinase Pathway
Cancer Res., December 15, 2009; 69(24): 9263 - 9270.
[Abstract] [Full Text] [PDF]

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 NEJMHome page
J. L. Mulshine and D. M. Jablons
Volume CT for Diagnosis of Nodules Found in Lung-Cancer Screening
N. Engl. J. Med., December 3, 2009; 361(23): 2281 - 2282.
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 CarcinogenesisHome page
M. Chen, A. Cassidy, J. Gu, G. L. Delclos, F. Zhen, H. Yang, M. A.T. Hildebrandt, J. Lin, Y. Ye, R. M. Chamberlain, et al.
Genetic variations in PI3K-AKT-mTOR pathway and bladder cancer risk
Carcinogenesis, December 1, 2009; 30(12): 2047 - 2052.
[Abstract] [Full Text] [PDF]

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 CarcinogenesisHome page
J. Niu, Y.-J. Huang, L.-E Wang, E. M. Sturgis, and Q. Wei
Genetic polymorphisms in the PTPN13 gene and risk of squamous cell carcinoma of head and neck
Carcinogenesis, December 1, 2009; 30(12): 2053 - 2058.
[Abstract] [Full Text] [PDF]

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 Anticancer ResHome page
W. YE, P. XU, W. R. THRELFALL, R. JEN, H. LI, S.-H. LIN, C.-T. KUO, and Y. C. LIN
Zeranol Enhances the Proliferation of Pre-adipocytes in Beef Heifers
Anticancer Res, December 1, 2009; 29(12): 5045 - 5052.
[Abstract] [Full Text] [PDF]

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 CJASNHome page
S. M. Bonsib
Renal Cystic Diseases and Renal Neoplasms: A Mini-Review
Clin. J. Am. Soc. Nephrol., December 1, 2009; 4(12): 1998 - 2007.
[Abstract] [Full Text] [PDF]

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 Mayo Clin Proc.Home page
S. K. Kumar, J. R. Mikhael, F. K. Buadi, D. Dingli, A. Dispenzieri, R. Fonseca, M. A. Gertz, P. R. Greipp, S. R. Hayman, R. A. Kyle, et al.
Management of Newly Diagnosed Symptomatic Multiple Myeloma: updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines
Mayo Clin. Proc., December 1, 2009; 84(12): 1095 - 1110.
[Abstract] [Full Text] [PDF]

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 ANN INTERN MEDHome page
J. S. Mandelblatt, K. A. Cronin, S. Bailey, D. A. Berry, H. J. de Koning, G. Draisma, H. Huang, S. J. Lee, M. Munsell, S. K. Plevritis, et al.
Effects of Mammography Screening Under Different Screening Schedules: Model Estimates of Potential Benefits and Harms
Ann Intern Med, November 17, 2009; 151(10): 738 - 747.
[Abstract] [Full Text] [PDF]

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 Am J EpidemiolHome page
Y. Lu, J. Prescott, J. Sullivan-Halley, K. D. Henderson, H. Ma, E. T. Chang, C. A. Clarke, P. L. Horn-Ross, G. Ursin, and L. Bernstein
Body Size, Recreational Physical Activity, and B-Cell Non-Hodgkin Lymphoma Risk Among Women in the California Teachers Study
Am. J. Epidemiol., November 15, 2009; 170(10): 1231 - 1240.
[Abstract] [Full Text] [PDF]

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 Clin. Cancer Res.Home page
M. Kashani-Sabet, S. Venna, M. Nosrati, J. Rangel, A. Sucker, F. Egberts, F. L. Baehner, J. Simko, S. P.L. Leong, C. Haqq, et al.
A Multimarker Prognostic Assay for Primary Cutaneous Melanoma
Clin. Cancer Res., November 15, 2009; 15(22): 6987 - 6992.
[Abstract] [Full Text] [PDF]

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 J Natl Compr Canc NetwHome page
T. B. Bevers, B. O. Anderson, E. Bonaccio, S. Buys, M. B. Daly, P. J. Dempsey, W. B. Farrar, I. Fleming, J. E. Garber, R. E. Harris, et al.
Breast Cancer Screening and Diagnosis
J Natl Compr Canc Netw, November 1, 2009; 7(10): 1060 - 1096.
[Full Text] [PDF]

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 Cancer Epidemiol. Biomarkers Prev.Home page
E. Sidelnikov, R. M. Bostick, W. D. Flanders, Q. Long, and M. E. Seabrook
Colorectal Mucosal Expression of MSH2 as a Potential Biomarker of Risk for Colorectal Neoplasms
Cancer Epidemiol. Biomarkers Prev., November 1, 2009; 18(11): 2965 - 2973.
[Abstract] [Full Text] [PDF]

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 ptjournalHome page
N. L. Stout
Cancer Prevention in Physical Therapist Practice
Physical Therapy, November 1, 2009; 89(11): 1119 - 1122.
[Full Text] [PDF]

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 JNMHome page
G. Ren, Z. Liu, Z. Miao, H. Liu, M. Subbarayan, F. T. Chin, L. Zhang, S. S. Gambhir, and Z. Cheng
PET of Malignant Melanoma Using 18F-Labeled Metallopeptides
J. Nucl. Med., November 1, 2009; 50(11): 1865 - 1872.
[Abstract] [Full Text] [PDF]


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