Complementary & Alternative Methods (CAM) refers to products and regimens that individuals may employ either to enhance wellness, relieve symptoms of disease and side-effects of conventional treatments, or cure disease. CAM articles provide evidence-based information on promising complementary and alternative methods, and inform clinicians of methods that may harm patients.

Environmental Carcinogens articles deal with actual, potential, or perceived environmental and workplace carcinogens. Authors should highlight ways to advise patients about environmental exposures known or perceived to cause cancer by providing clear, concise information and advice that is based on laboratory and epidemiological research.

Emerging Trends in Basic Science articles cover issues related to basic research (including molecular and cellular biology, epidemiology, immunology, radiation physics and biology, information technology, and related fields). They should be geared toward clinicians with limited time who want to remain up-to-date on advances in basic science research and the current and future clinical implications of that research.

News & Views appear in each issue and feature practical, concise, usable news designed for clinicians and their patients. The goal of this section is to inform, spark interest, and enhance communication and interaction among readers. This section is written in-house and external submissions are not accepted.

Patient Pages are written to provide general information on specific topics for patients and caregivers, Patient Pages are usually related to the content of the particular issue in which they appear. Patient Pages may be photocopied and given directly to patients. This section is written in-house and external submissions are not accepted.

Supplements

CA requires submission of an outline, which includes details on length, subject, authors (if available), and sponsorship information. Any supplement information that is received without the aforementioned items will be returned. This information must be provided for consideration by the Editors to determine appropriateness for CA's audience. All editorial materials, including supplements, are subject to peer review, and there is no guarantee of publication. All supplement costs must be borne by the authors or sponsoring group. Financial disclosures related to support should be provided in the cover letter.

Peer-review Process

Manuscripts that adhere to submission guidelines are initially reviewed by the Editor of CA. Manuscripts qualifying for peer review are sent to at least two expert reviewers. The corresponding author will receive all editorial communications regarding the status of the manuscript, revisions, and reviews. All revisions and the dissemination of the reviewers’ comments and other manuscript information to co-authors are the corresponding author’s responsibility.

Pre-submission Requirements: Unsolicited Manuscripts

CA requires all pre-submissions to contain an article outline and abstract for review by the Editors before any unsolicited manuscript can be submitted for peer review. All pre-submissions that do not contain this information will be returned without review. Please e-mail an abstract, full author list, manuscript length, and information about the author to the Editorial Office for consideration (see Editorial Office contact information below).

Submission Guidelines

Material submitted to CA must be original and not published or submitted for publication elsewhere. Copies of any related in press publications should accompany manuscripts submitted to CA.

Online Submission Procedure

CA uses ScholarOne Manuscripts (formerly known as Manuscript Central), a Web-based, peer-review tracking system, for online submission of all manuscripts.

Authors are required to submit the following manuscript information online using ScholarOne Manuscripts (formerly known as Manuscript Central):

• corresponding author’s contact information (a valid e-mail address is required)
• manuscript title
• abstract
• cover letter
• suggested reviewers/reviewers not to use
• keywords
• acknowledgments

Once a manuscript has been submitted online, an e-mail acknowledgment will be sent. Authors can check the status of a manuscript at any time by logging on to ScholarOne Manuscripts (formerly known as Manuscript Central).

Page Proofs (for Accepted Articles only)

Page proofs are received by the corresponding author directly from the publisher (via e-mail) and must be returned within 48 hours of receipt. Make any corrections to the article using Adobe PDF markup tools and e-mail the proof corrections to the contact person provided within 48 hours. It is the corresponding author's responsibility to consult with co-authors regarding the proofs. Substantial author revisions during this stage of production may incur additional costs, which must be borne by the authors. Excessive corrections must be reviewed and authorized by the Editorial Office.

Definition of Authorship

The journal's definition of what qualifies as authorship is based on the Uniform Requirements for Manuscripts Submitted to Biomedical Journals,¹ established by the International Committee of Medical Journal Editors (ICMJE). Authors are those who have contributed to the conception and design of the article, the acquisition of data, or the analysis and interpretation of data, as well as the writing of the article or the revision of its content; and have read and approved the final version of the article before submission.

All listed authors must sign the copyright transfer agreement. In doing so, each author takes public responsibility for the article’s content. No article will be published without a copyright transfer agreement signed by all the listed authors. Failure to submit this form at the time the manuscript is submitted can cause delays in peer review and publication. The signed copyright transfer agreement should be scanned and submitted as a PDF file along with the manuscript file via ScholarOne Manuscripts (formerly known as Manuscript Central). Copyright transfer agreements should be uploaded as PDF files with their submissions under "Supplementary Material Not for Review."

Disclosures

Authors are required to disclose all relevant financial support and potential conflicts of interest in their cover letter, within the manuscript, and on the copyright transfer agreement form. If there are no financial disclosures from any authors, this should be stated as well. In addition, authors have an ethical responsibility to ensure all research discussed in their work is credible and data are accurate prior to publication. Authors must also clearly identify, within the manuscript, any discussion of investigational or "off-label" use of drugs or medical devices. The authors will be required to submit such disclosures when submitting their manuscript using ScholarOne Manuscripts (formerly known as Manuscript Central).

Acknowledgments

All others who contributed to the work should be listed under Acknowledgments. This includes people who provided purely technical help, writing assistance, or general support.

All financial support should be clearly acknowledged in the manuscript, as well as any details regarding the role of the funding organization in the creation of the manuscript.

Corresponding Author Responsibilities

The corresponding author is the point of contact for the Editorial Office and Publisher. He or she is responsible for:

• Collecting signed copyright transfer agreements and CME disclosure forms (if the manuscript is associated with a CME quiz) from all authors and submitting these to the Editorial Office with the manuscript.
• Sharing the reviewers’ comments with the other authors and ensuring the requested revisions are made or clearly disputed before resubmitting the manuscript.
• Page proofs. The publisher will e-mail page proofs to the corresponding author. It is up to the corresponding author to share these proofs with the other authors. The corresponding author is responsible for incorporating all the corrections made by the authors and returning the proofs to the publisher within 48 hours.
• Reviewing the CA cover. The corresponding author of the article featured on the cover of an issue of CA will receive PDF files of cover designs from the Editorial Office. He or she may share these designs with the other authors, but the corresponding author is responsible for ensuring any figure/tables/illustrations taken from the article (or supplied specifically for use on the cover) have been reproduced clearly and accurately, and for verifying the accuracy of their use for the Editorial Office.

National Institutes of Health (NIH) Mandate

NIH authors should be aware that they will receive an e-mail request once Wiley-Blackwell has posted the files of their accepted manuscript to the NIH Manuscript Submission system to approve the upload for display on the PubMed Central system. This is a requirement of their grant/affiliation.

For NIH employees only, we will accept the NIH Publishing Agreement.

Manuscript Format

Manuscripts should follow the AMA Manual of Style (10th ed.)² for grammar, punctuation, and style, and should meet the Uniform Requirements for Manuscripts Submitted to Biomedical Journals¹ established by the ICMJE for general authorship guidelines.

Text must be submitted in Word (.doc or .rtf) format. Do not embed tables or figures. Please include the title page, synopsis, abstract, main body, references, acknowledgments, and figure legends in a single file.

Note: This journal does not accept Microsoft Word 2007 documents at this time. Please save your document as an older (.doc) file type.

Title Page

This should include:

• A brief, specific title
• All authors listed by first name, last name
• The corresponding author’s name and contact information
• The total number of text pages (including title page, references, and figure legends), tables, and illustrations
• Acknowledgment of all sources of financial support or financial interest in products or manufacturers of products mentioned in the article (if there are no financial disclosures from any authors, this should be stated as well)
• Acknowledgment of any contributors who do not qualify as authors (see above)

A secondary page detailing all author names, including academic degrees, titles, affiliations, and current addresses must be provided. This information will be published on the first page of the article along with the financial disclosure statement.

Abstract Page

If applicable, the abstract should be brief (200 words maximum) and present an accurate overview of the manuscript. Four to six keywords should be listed at the bottom of the page. Please use Index Medicus subject headings.

Text

The manuscript should be typed, double-spaced, with 1-inch margins. Use footnotes only in tables and figures, not to elaborate on the article text. Consult the Physicians’ Desk Reference³ to verify drug names (use generic names only, adding the brand name afterward in parentheses if relevant). Abbreviations and/or acronyms should be spelled out in full and abbreviated in parentheses on first use in the text.

References

References should be numbered consecutively according to the order in which they are cited in the text. A reference cited only in a table or figure is numbered within the sequence established by the first mention of that table or figure in the text.

References must be current. Use of references more than 10 years old is discouraged unless they are classic or unique works.

Authors must verify all references. The reference list should follow the text of the manuscript. Follow the AMA Manual of Style (10th ed.)² for reference formatting and punctuation.

In the reference list, abbreviate names of journals according to MEDLINE/Index Medicus. For six or more authors, list the first three names followed by "et al." Please note the following examples for format and punctuation:

Journal
1. Jemal A, Siegel R, Ward E, et al. Cancer Statistics, 2008. CA Cancer J Clin. 2008;58:71-96.

Book
2. Eifel PJ, Levenback C. American Cancer Society Atlas of Clinical Oncology: Cancer of the Female Lower Genital Tract. Hamilton, Ontario: BC Decker; 2001.

Chapter in a book
3. Park BH, Vogelstein B. Tumor-Suppressor Genes. In: Kufe DW, Pollock RE, Weichselbaum RR, et al, eds. Cancer Medicine. 6th ed. Hamilton, Ontario: BC Decker; 2003:87-106.

Web site
4. Health on the Net Foundation. Health on the Net Foundation code of conduct (HONcode) for medical and health Web sites. Available at: http://www.hon.ch/HONcode/Conduct.html. Accessed August 26, 2003.

Tables

Tables must be created using the table tool in Word (.doc or .rtf). Each table must be in a separate file, and the files should be named by table # (i.e., table 1, table 2, etc.). Number the tables consecutively in the order in which they are cited in the text. Include a brief descriptive title for each table. Do not use bulleted lists in tables. Do not embed tables in the manuscript text.

Figures and Illustrations

Authors are encouraged to submit their figure files in color. There is no charge associated with color figures.

Number figures consecutively according to the order in which they are cited in the text. The figures should immediately follow the tables in the manuscript. Each file must contain a single figure and be named by figure # (i.e., figure 1, figure 2, etc.). Files containing individual panels will not be accepted. Figures must be in .tif or .eps format. Do not embed figures in the manuscript text.

Figures (line art): Electronic Formatting